Table 1

Comparable immunogenicity between different etanercept biosimilars

Samsung Benepali (SB4)26 Sandoz Erelzi (GP2015)27*Coherus (CHS0214)28
SB4EnbrelGP2015EnbrelCHS0214Enbrel
ADA + (Week 8)2 (0.7%)38 (12.8%)05 (1.9%)XX
ADA + (Week 24)2 (0.7%)39 (13.2%)05 (1.9%)1.3%4.7%
ADA + (Week 52)3 (1.0%)39 (13.2%)05 (1.9%)XX
nAb + (Week 8)0100XX
nAb + (Week 24)010000
nAb + (Week 52)0100XX
  • X means not stated. *Data for study 302 in patients with psoriasis. ADA, anti‚ÄČdrug antibody; nAb, neutralising‚ÄČantibody.